Germline genomics
نویسندگان
چکیده
منابع مشابه
Germline genomics.
The completion of the C. elegans genome sequence permits the comprehensive examination of the expression and function of genes. Annotation of virtually every encoded gene in the genome allows systematic analysis of those genes using high-throughput assays, such as microarrays and RNAi. This chapter will center on the use of microarrays to comprehensively identify genes with enriched expression ...
متن کاملUsing germline genomics to individualize pediatric cancer treatments.
The amazing successes in cure rates for children with cancer over the last century have come in large part from identifying clinical, genetic, and molecular variables associated with response to therapy in large cooperative clinical trials and stratifying therapies according to the predicted risk of relapse. There is an expanding interest in identifying germline genomic variants, as opposed to ...
متن کاملGermOnline 4.0 is a genomics gateway for germline development, meiosis and the mitotic cell cycle
GermOnline 4.0 is a cross-species database portal focusing on high-throughput expression data relevant for germline development, the meiotic cell cycle and mitosis in healthy versus malignant cells. It is thus a source of information for life scientists as well as clinicians who are interested in gene expression and regulatory networks. The GermOnline gateway provides unlimited access to inform...
متن کاملCharacteristics of Germline and Non-germline Retinoblastomas
PURPOSE To discuss the clinical characteristics, treatment and outcomes of germline and non-germline retinoblastoma tumors. METHODS A retrospective study was performed on retinoblastoma cases from 1979 to 2007. General characteristics of the patients, treatment modalities, histopathological findings and survival were compared in germline versus non-germline cases. RESULTS We analyzed 557 ca...
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ژورنال
عنوان ژورنال: WormBook
سال: 2006
ISSN: 1551-8507
DOI: 10.1895/wormbook.1.74.1